Novel Solutions Make for Healthy Animals

Osteoarthritis occurs in 20% of dogs usually because of a previous injury. This form of osteoarthritis is known as post traumatic osteoarthritis. The current treatment for dog OA is pain management. But long-term use of these methods cause deadly side-effects. Surveys of pet owners show that they are looking for effective treatments for their companions. Indeed, pet owners have shown an increased interest in animal acupuncture to help their pets with the pain and stiffness of OA.

ProteaPex Therapeutics is developing an innovative disease modifying therapeutic technology to treat osteoarthritis in companion animals. Extracellular Matrix Protection Factor (ECPF) is a novel, safe and effective intra-joint injection that reduces the pain and damage caused by osteoarthritis. ECPF-1, our lead molecule, has shown promising results in an animal model of post traumatic osteoarthritis:

  1. No cellular toxicity was noted
  2. Tissue destruction was diminished
  3. Animal mobility was increased
  4. Overall joint health was improved

What Causes Canine osteoarthritis?
Canine arthritis can occur as a result of:
  • A joint infection
  • Dislocation
  • Trauma
  • An inherited condition, such as hip dysplasia
  • Immune system problems
  • Obesity
  • Ligament, tendon or muscle injury
  • Fracture of bone that involves a joint
  • Aging and natural erosion of cartilage
***If a larger dog suffers any injuries or sprains during his growth period, this can cause him to develop arthritis later in life.

Model of Extracellular Matrix Protection Factor (ECPF) in the treatment of osteoarthritis

How Is Canine Osteoarthritis Diagnosed?

A veterinarian may conduct a physical exam, take radiographs and perform other diagnostic tests to help determine the cause of your dogís pain. He or she will also check your dogís medical history for previous injuries and consider possible inherited conditions.

How Can Canine Arthritis Be Treated?

Once symptoms of arthritis set in, there is no cure. Itís important for you to work with your veterinarian to create a program to minimize your dogís pain while keeping him healthy. Some general treatment options may include:

*** Please do not give your dog human medication without first checking with your vet.


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