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ECPF-1

Novel Solutions for Health

Osteoarthritis occurs in 20% of humans and dogs usually because of a previous injury. This form of osteoarthritis is known as post traumatic osteoarthritis. The current treatment for OA is pain management. But long-term use of these methods causes dangerous side-effects.

ProteaPex Therapeutics is developing an innovative disease modifying therapeutic technology to treat osteoarthritis. Extracellular Matrix Protection Factor (ECPF) is a novel, safe and effective intra-joint injection that reduces the pain and damage caused by osteoarthritis. ECPF-1, our lead molecule, has shown promising results in an animal model of post traumatic osteoarthritis:

  1. No cellular toxicity was noted
  2. Tissue destruction was diminished
  3. Animal mobility was increased
  4. Overall joint health was improved

What Causes Osteoarthritis?

Osteoarthritis can occur as a result of:

  • A joint infection
  • Dislocation
  • Trauma
  • An inherited condition, such as hip dysplasia
  • Immune system problems
  • Obesity
  • Ligament, tendon or muscle injury
  • Fracture of bone that involves a joint
  • Aging and natural erosion of cartilage

How Is Canine Osteoarthritis Diagnosed?

A veterinarian may conduct a physical exam, take radiographs and perform other diagnostic tests to help determine the cause of your dog’s pain. He or she will also check your dog’s medical history for previous injuries and consider possible inherited conditions.

How Can Canine Arthritis Be Treated?

Once symptoms of arthritis set in, there is no cure. It’s important for you to work with your veterinarian to create a program to minimize your dog’s pain while keeping him healthy. Some general treatment options may include:

  • The use of antibiotics, painkillers or anti-inflammatory medications
  • The use of nutritional supplements to help replenish cartilage
  • Healthy diet and regular, low-impact exercise
  • Weight loss, if required

*** Please do not give your dog human medication without first checking with your vet.

Surveys of pet owners show that they are looking for effective treatments for their companions. Indeed, pet owners have shown an increased interest in animal acupuncture to help their pets with the pain and stiffness of OA.

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